{"id":7264,"date":"2013-07-23T19:08:00","date_gmt":"2013-07-24T00:08:00","guid":{"rendered":"http:\/\/medicinainterna.com.mx\/?p=7264"},"modified":"2013-07-23T19:08:00","modified_gmt":"2013-07-24T00:08:00","slug":"sistema-internacional-de-puntuacion-pronostica-international-prognostic-scoring-system-ipss-del-smd","status":"publish","type":"post","link":"https:\/\/medicinainterna.com.mx\/?p=7264","title":{"rendered":"Sistema Internacional de Puntuaci\u00f3n Pron\u00f3stica (International Prognostic Scoring System, IPSS) del SMD."},"content":{"rendered":"

<\/h3>\n\n\n\n\n\n
\n

Sistema Internacional de Puntuaci\u00f3n Pron\u00f3sticaa<\/p>\n<\/td>\n<\/tr>\n

Variable pron\u00f3stica<\/td>\n\n

0<\/p>\n<\/td>\n

\n

0, 5<\/p>\n<\/td>\n

\n

1, 0<\/p>\n<\/td>\n

\n

1, 5<\/p>\n<\/td>\n

\n

2, 0<\/p>\n<\/td>\n<\/tr>\n

Blastos en m\u00e9dula \u00f3sea (%)<\/p>\n

Citogen\u00e9tica *<\/p>\n

Citopenias<\/td>\n

\n

< 5<\/p>\n

Buena<\/p>\n

0\/1<\/p>\n<\/td>\n

\n

5-10<\/p>\n

Intermedia<\/p>\n

2\/3<\/p>\n<\/td>\n

\n

–<\/p>\n

Mala<\/p>\n

–<\/p>\n<\/td>\n

\n

11-20<\/p>\n

–<\/p>\n

–<\/p>\n<\/td>\n

\n

21-30<\/p>\n

–<\/p>\n

–<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

* Buena = normal, p\u00e9rdida del cromosoma Y, delecci\u00f3n 5q aislada, delecci\u00f3n 20q. Intermedia = otras anomal\u00edas<\/p>\n

Mala = tres o m\u00e1s anomal\u00edas, anomal\u00edas del cromosoma 7.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n\n\n\n\n\n
Categor\u00edas de supervivencia y riesgo seg\u00fan el grupo IPSS<\/i><\/td>\n<\/tr>\n
 <\/td>\n\n

0<\/p>\n<\/td>\n

\n

0,5-1,0<\/p>\n<\/td>\n

\n

1,5-2<\/p>\n<\/td>\n

\n

>2,5<\/p>\n<\/td>\n<\/tr>\n

Desarrollo de LMA a lo largo de la vida<\/p>\n

Mediana de a\u00f1os hasta LMA<\/p>\n

Supervivencia mediana (a\u00f1os)<\/td>\n

\n

19%<\/p>\n

9,4<\/p>\n

5,7<\/p>\n<\/td>\n

\n

30%<\/p>\n

3,3<\/p>\n

3,5<\/p>\n<\/td>\n

\n

33%<\/p>\n

1,1<\/p>\n

1,2<\/p>\n<\/td>\n

\n

45%<\/p>\n

0,2<\/p>\n

0,4<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

La puntuaci\u00f3n pron\u00f3stica es importante para determinar el abordaje terap\u00e9utico y las metas terap\u00e9uticas. En pacientes de riesgo bajo a intermedio-1, que tienen m\u00e1s probabilidad de tener per\u00edodos de supervivencia largos, los tratamientos que ofrecen mejor\u00edas prolongadas a largo plazo en los recuentos hematol\u00f3gicos y mejoran el nivel de salud son una prioridad. En las categor\u00edas de mayor riesgo, la prioridad son los tratamientos agresivos que alargan la supervivencia y retrasan la progresi\u00f3n a LMA.<\/p>\n

Fuente: Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 997;89:2079-2088<\/p>\n","protected":false},"excerpt":{"rendered":"

Sistema Internacional de Puntuaci\u00f3n Pron\u00f3sticaa Variable pron\u00f3stica 0 0, 5 1, 0 1, 5 2, 0 Blastos en m\u00e9dula \u00f3sea (%) Citogen\u00e9tica * Citopenias < 5 Buena 0\/1 5-10 Intermedia 2\/3 – Mala – 11-20 – – 21-30 – –   * Buena = normal, p\u00e9rdida del cromosoma Y, delecci\u00f3n 5q aislada, delecci\u00f3n 20q. Intermedia … Continue reading “Sistema Internacional de Puntuaci\u00f3n Pron\u00f3stica (International Prognostic Scoring System, IPSS) del SMD.”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-7264","post","type-post","status-publish","format-standard","hentry","category-hematologia"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts\/7264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7264"}],"version-history":[{"count":0,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts\/7264\/revisions"}],"wp:attachment":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}