{"id":7230,"date":"2013-07-23T18:58:15","date_gmt":"2013-07-23T23:58:15","guid":{"rendered":"http:\/\/medicinainterna.com.mx\/?p=7230"},"modified":"2013-07-23T18:58:15","modified_gmt":"2013-07-23T23:58:15","slug":"clasificacion-de-las-alteraciones-hemostaticas-y-las-causas-de-sangrado-patologico","status":"publish","type":"post","link":"https:\/\/medicinainterna.com.mx\/?p=7230","title":{"rendered":"Clasificaci\u00f3n de las alteraciones hemost\u00e1ticas y las causas de sangrado patol\u00f3gico."},"content":{"rendered":"

\n\n\n\n\n
1. Alteraci\u00f3n de las plaquetas:
\n1.1. Alteraciones cuantitativas (trombocitopenia):
\n1.1.1. Trombopoyesis insuficiente o anormal:
\n1.1.1.1. Anemia apl\u00e1sica.
\n1.1.1.2. D\u00e9ficit de B12 o de folato.
\n1.1.2. Destrucci\u00f3n acelerada, p\u00e9rdida o distribuci\u00f3n anormal:
\n1.1.2.1. Inmunol\u00f3gico: p\u00farpura trombocitop\u00e9nica idiop\u00e1tica, drogas.*
\n1.1.2.2. No inmunol\u00f3gica: p\u00farpura tromb\u00f3tica trombocitop\u00e9nica,* coagulaci\u00f3n intravascular diseminada.*
\n1.2. Alteraciones cualitativas:
\n1.2.1. Cong\u00e9nitas:
\n1.2.1.1. Defectos de adhesi\u00f3n: enfermedad de von Willebrand.
\n1.2.1.2. Defectos de secreci\u00f3n: enfermedad de almacenamiento de las plaquetas.
\n1.2.1.3. Defecto de agregaci\u00f3n: tromboastenia.
\n1.2.2. Adquiridas:
\n1.2.2.1. Defectos de adhesi\u00f3n: uremia,* drogas.*
\n1.2.2.2. Defectos de secreci\u00f3n: enfermedad mieloproliferativa, drogas.*
\n1.2.2.3. Defecto de agregaci\u00f3n: paraproteinemia, drogas,* productos de degeneraci\u00f3n de fibrina\/fibrin\u00f3geno.*
\n2. Alteraciones de la coagulaci\u00f3n:
\n2.1. Deficiencia de factores:
\n2.1.1. Defectos de producci\u00f3n:
\n2.1.1.1. Cong\u00e9nito: hemofilia.
\n2.1.1.2. Adquirido: d\u00e9ficit de vitamina K,* enfermedades hep\u00e1ticas,* drogas\u00a0 (cumar\u00ednicos).*
\n2.1.2. Destrucci\u00f3n acelerada:
\n2.1.2.1. Consumo: fibrinolisis, coagulaci\u00f3n intravascular diseminada.*
\n2.1.2.2. P\u00e9rdida: s\u00edndrome nefr\u00f3tico.
\n2.1.2.3. Multifactorial: postoperatorio de cirug\u00eda card\u00edaca.
\n2.1.3. Dilucional: reposici\u00f3n masiva de sangre.*
\n2.2. Inhibidores (anticoagulantes):
\n2.2.1. Anticuerpos contra factores de coagulaci\u00f3n: inhibidor factor VIII.
\n2.2.2. Anticuerpos anti fosfol\u00edpidos: inhibidor “lupuslike”.
\n2.2.3. Disproteinemia.
\n2.2.4. Productos de degeneraci\u00f3n de fibrina\/fibrin\u00f3geno.*
\n2.2.5. Heparina*.<\/td>\n<\/tr>\n
(*) alteraciones comunes en UCI.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Fuente: Ansell JE. Acquired bleeding disorders. En: Rippe JM, Irwin RS, Fink MP, Cerra FB (eds.): Intensive Care Medicine (3rd ed). Little, Brown. 1996: 1357-1368<\/p>\n","protected":false},"excerpt":{"rendered":"

1. Alteraci\u00f3n de las plaquetas: 1.1. Alteraciones cuantitativas (trombocitopenia): 1.1.1. Trombopoyesis insuficiente o anormal: 1.1.1.1. Anemia apl\u00e1sica. 1.1.1.2. D\u00e9ficit de B12 o de folato. 1.1.2. Destrucci\u00f3n acelerada, p\u00e9rdida o distribuci\u00f3n anormal: 1.1.2.1. Inmunol\u00f3gico: p\u00farpura trombocitop\u00e9nica idiop\u00e1tica, drogas.* 1.1.2.2. No inmunol\u00f3gica: p\u00farpura tromb\u00f3tica trombocitop\u00e9nica,* coagulaci\u00f3n intravascular diseminada.* 1.2. Alteraciones cualitativas: 1.2.1. Cong\u00e9nitas: 1.2.1.1. Defectos de adhesi\u00f3n: … Continue reading “Clasificaci\u00f3n de las alteraciones hemost\u00e1ticas y las causas de sangrado patol\u00f3gico.”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-7230","post","type-post","status-publish","format-standard","hentry","category-hematologia"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts\/7230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7230"}],"version-history":[{"count":0,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=\/wp\/v2\/posts\/7230\/revisions"}],"wp:attachment":[{"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicinainterna.com.mx\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}